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TVIS30016686
Basic Information
VIS ID
TVIS30016686
Fusion event
HIV-GTF3C4 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.13
Reference genome
GRCh37/hg19
Start
135553991/132678604 (Hg38)
End
135554282/132678604 (Hg38)
Orient
+
Location type
Exonic
Target gene
GTF3C4
miRNAs that regulate target gene
hsa-mir-30a-5p
;
hsa-mir-16-5p
;
hsa-let-7b-5p
;
hsa-mir-615-3p
;
hsa-mir-331-3p
;
hsa-mir-320a
;
hsa-let-7e-3p
;
hsa-mir-571
;
hsa-mir-3173-3p
;
hsa-mir-4259
;
hsa-mir-4428
;
hsa-mir-4477b
;
hsa-mir-6891-5p
;
hsa-mir-875-3p
;
hsa-mir-489-3p
;
hsa-let-7d-3p
;
hsa-mir-3913-3p
;
hsa-mir-873-5p
;
hsa-mir-1299
;
hsa-mir-642a-5p
;
hsa-mir-4487
;
hsa-mir-558
;
hsa-mir-3160-3p
;
hsa-mir-6846-3p
;
hsa-mir-494-3p
;
hsa-mir-6128
;
hsa-mir-6751-3p
;
hsa-mir-1199-5p
;
hsa-mir-1251-5p
;
hsa-mir-3925-3p
;
hsa-mir-766-3p
;
hsa-mir-1304-3p
;
hsa-mir-6769b-3p
;
hsa-mir-4723-3p
;
hsa-mir-3183
;
hsa-mir-4308
;
hsa-mir-2276-5p
;
hsa-mir-6892-3p
;
hsa-mir-1324
;
hsa-mir-1182
;
hsa-mir-3184-3p
;
hsa-mir-3646
;
hsa-mir-130a-5p
;
hsa-mir-186-3p
;
hsa-mir-188-5p
;
hsa-mir-23a-3p
;
hsa-mir-23b-3p
;
hsa-mir-23c
;
hsa-mir-28-5p
;
hsa-mir-3139
;
hsa-mir-3606-3p
;
hsa-mir-4282
;
hsa-mir-4633-3p
;
hsa-mir-513a-3p
;
hsa-mir-513c-3p
;
hsa-mir-610
;
hsa-mir-6500-5p
;
hsa-mir-6715a-3p
;
hsa-mir-6715b-3p
;
hsa-mir-6866-3p
;
hsa-mir-708-5p
Nearest miRNA
hsa-let-7a-1/Upstream/2052241; hsa-mir-126/Downstream/267103;
Nearest TSS
ENST00000422679/Upstream/8203;
ENST00000372136/Downstream/48994;
Nearest CpG islands
None/Target,
chr9-CpG: 64/Upstream/7529
,
chr9-CpG: 25/Downstream/30063
Upstream sequence
GGAAAAGAATCCATCTCTTCATGCAACACAATTGAGTCAGGAATCACCTCTCCCAGTGTATTGTTTTGGTGGGAATATGAGCACAATAATCGAAAAATGA
Downstream sequence
TTGTCTCCATGACTGCAGACAAACAGAATGGAACAGTCTATACTTGCTCCAGTGACGGAAAGGTGAGGCAGCTGATTCCCATTTTCACAGATGTTGCATT
Target sequence
GTGGCCTTATTGTGGGGAGTGCTTTTGGACCCATAAAAATTCTTCCTGTCAATCTCAAAGCAGTCAAAGGCTATTTCACTTTAAGGCAGCCTGTTATCTTGTGGAAAGAAATGGACCAGTTACCTGTGCACAGTATCAAATGTGTGCCACTTTATCATCCTTACCAGAAGTGTAGTTGCAGCTTAGTAGTGGCTGCAAGAGGCTCTTATGTATTTTGGTGTCTTCTTCTGATCTCCAAAGCAGGGCTGAATGTTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT5
Sample type
PBMC
Age
44
Gender
Male
CpG Island Information
×
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