Basic Information
VIS ID
TVIS30016690
Fusion event
HIV-FBXW5 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.3
Reference genome
GRCh37/hg19
Start
139836363/136941911 (Hg38)
End
139836513/136941911 (Hg38)
Orient
+
Location type
Intronic
Target gene
FBXW5
Nearest miRNA
hsa-let-7a-1/Upstream/55108; hsa-mir-3621/Downstream/227275;
Nearest TSS
ENST00000422679/Upstream/20786; ENST00000371634/Downstream/757;
Nearest CpG islands
chr9-CpG: 307/Target, None/Upstream, None/Downstream
Upstream sequence
CGGGGGCCCCAGACCTGAATCAGGCCCGTCGGTTGCTTGCTGGCCAGCGGCCCTGCCTGCGTTTGTTTTCACTGCTCATCCCACAGGCCCCAGGTCTGGG
Downstream sequence
GTAGGTGAGGCAGCCAGTGGTGAAGATGAGGTACTTGCTCTTGGCGCCTGTGGCACTGCGCTCGGGTGGCTTGGTGTGGCCCTGGGCCAGCAGCTCGGCC
Target sequence
CTTGTGACCCCAGGGGCGAGTGAACGATCCCAGCTTTGCCTGTGGACTTGCTTGCTGTCTGCCCCTCAGGACCCCTGCCCGGCCTCCCCCAAGCTCCTAGGACCGAGGCGGGCAGCATGGCGGCAGGGGTGTACCGATCTGGTGTGGGGA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate