Basic Information
VIS ID
TVIS30016716
Fusion event
HIV-chrX integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
13041032/13022913 (Hg38)
End
13041329/13022913 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-3690-1/Upstream/1704227; hsa-let-7f-2/Downstream/567379;
Nearest TSS
ENST00000429181/Upstream/47255; ENST00000568788/Downstream/20275;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/46433, chrX-CpG: 52/Downstream/355856
Nearby gene
FAM9C(No orient, 12703)
Upstream sequence
GTGATCCAAGGGAGAAGATTCTTAAATTATGTTCAATTGAATGTACACATCCAAACGTGGCTTAGCTTCTTTATGTCTTATGCTGTAAGAGTCTTTTTAT
Downstream sequence
GCTCTCAACAGATGTTGGCAGCTGCCTTTCCCTCAAGGTCCCACCTCCCCCACCCCAGACTTCCAGACACAGGCAGCTCAGGACATTTTCGTACTTTGTG
Target sequence
GATTTGTTTTGATTTTTATGTTTTTTAAATTTTTCTAGGATATGTGCTTGATAGTACTGAAACAAAGGCAGAAAAGAATCCTGGGGTAGGGGGGTGAGTGGGAGGGAAGTCTCTTTAAGGTCAAATTGAGTTACTGTCTCTTGCAGATGAAGATGAATATGCTCTCTCTCACCAGACAGATTCTTGTGGCCCACGGAGAAATCTGAGCTAGTTCCCTTTTCTTGCTAATGAAGGGTCATCACTGAGGAGACTGAA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate