Basic Information
VIS ID
TVIS30016751
Fusion event
HIV-chrX integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.11
Reference genome
GRCh37/hg19
Start
24097640/24079523 (Hg38)
End
24097681/24079523 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-23c/Upstream/4062336; hsa-let-7f-2/Downstream/4416032;
Nearest TSS
ENST00000429181/Upstream/6261; ENST00000497813/Downstream/69650;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/24505, chrX-CpG: 166/Downstream/69662
Nearby gene
EIF2S3(No orient, 713)
Upstream sequence
TGCATATgtaaatcctcttggctctactgtcaagatattttcaaaatctttttagttctgatcacttccactgctaccaccttagtcaaagccatcagtg
Downstream sequence
cttgccctgctgcagtctgttctcaacacgatagccagagtCCCTGTTTTTTAGAGAATACTACATACAACTCTGTGATAGTAAGGTGTAAAAGTTAGCC
Target sequence
actctcacctggactagccttctaactgtcctgcttctgca
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate