Basic Information
VIS ID
TVIS30016762
Fusion event
HIV-JPX integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
73195236/73975401 (Hg38)
End
73195455/73975401 (Hg38)
Orient
+
Location type
Intronic
Target gene
JPX
Nearest miRNA
hsa-let-7f-2/Upstream/3952478; hsa-mir-105-1/Downstream/242976;
Nearest TSS
ENST00000429181/Upstream/26428; ENST00000339534/Downstream/36067;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/412072, chrX-CpG: 41/Downstream/129928
Upstream sequence
tttctttctccattaaacacttgatgggaatttaagtagtttctgtgttttggcaattatcaattatgcgtctgttgacattcatgtggaaatatttaag
Downstream sequence
ttgcatttccttaatgactaatggagtaggaaatatttcatgttcttattagccattcttctttggtgaaatgtgtatttaaatcttttgcataattttt
Target sequence
cggacgtgctttcatttctcttatgtaggattttttggataatatggtaatttgactttttaagaatctggcaaactcttttccaaagtgactgtactacattacattcctatcagcaatatatgagggttagtgattttctacatatttgtctacatttattactgtcttttattaaaaccatttttgtgaaagtaaaattatctcattgtggtttta
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate