Basic Information
VIS ID
TVIS30016767
Fusion event
HIV-chrX integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
78396521/79141024 (Hg38)
End
78396351/79141024 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7f-2/Upstream/239775; hsa-mir-105-1/Downstream/5084728;
Nearest TSS
ENST00000429181/Upstream/195603; ENST00000276077/Downstream/3639;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/1001229, chrX-CpG: 27/Downstream/1194197
Nearby gene
GPR174(No orient, 29947)
Upstream sequence
cacattgccaactctcaggtcataaaatacctttgtcattCATAAAAAAGTATTTTACTTAAACAAGGAATGAATATAATTAGTACTTTAACTCATAACT
Downstream sequence
CCCACCCCAAAATAATTTGAATAACTGATTTTTAAAATGTTTTTTAATCCTTTAATTGTAGCACTCTTATATTTTATTGATGTTGATTAGTTAATTCTAT
Target sequence
tatggagttgttttgatgaataaataaaataatgattgtaaaacacattcatatcaaacacaatgcctggcacattgccaactctcaggtcataaaatacctttgtcattCATAAAAAAGTATTTTACTTAAACAAGGAATGAATATAATTAGTACTTTAACTCATAACT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate