Basic Information
VIS ID
TVIS30016768
Fusion event
HIV-WDR44 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q24
Reference genome
GRCh37/hg19
Start
117558931/118424968 (Hg38)
End
117558982/118424968 (Hg38)
Orient
+
Location type
Intronic
Target gene
WDR44
miRNAs that regulate target gene
hsa-mir-192-5p
Nearest miRNA
hsa-let-7f-2/Upstream/38497; hsa-mir-105-1/Downstream/1221770;
Nearest TSS
ENST00000429181/Upstream/32220; ENST00000633080/Downstream/70930;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/78443, chrX-CpG: 17/Downstream/70199
Upstream sequence
ttatttttgtatatgatgtaatataagagtccaatttcatttttttgcatgtgtatctccaAAggtaatcagttttgtgaagaaaagtaaaacaaagtgg
Downstream sequence
tgttcgagcaaagtacaaaggaggtaaggaaatgatcatatgataagaccattccaggtagagacagcagcaagtgaagctgctataaggcaggagttct
Target sequence
gatggcagggagtaaataaggtgggtgagcaaagcttcactgagaagttgt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate