Basic Information
VIS ID
TVIS30016771
Fusion event
HIV-chrX integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q25
Reference genome
GRCh37/hg19
Start
123471546/124337696 (Hg38)
End
123471769/124337696 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7f-2/Upstream/2966643; hsa-mir-105-1/Downstream/9831682;
Nearest TSS
ENST00000429181/Upstream/5036; ENST00000360027/Downstream/8648;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/4349, chrX-CpG: 17/Downstream/865225
Nearby gene
SH2D1A(No orient, 8585)
Upstream sequence
GGCTGGTTTTATGATACTCATGTGGGCTGATAGCTCCTTGGAATTTTGGGAAGATGGGATACAGATGAGACTTGGACATGTTTCAGCATAATCCATTTTC
Downstream sequence
CATACATGCAAGAaaaggcagcaggtttctgtggcataaacctgggctttggagacagagaaaacgagttcaactacttgatctattattcagtagctgt
Target sequence
GTATACCAGCAGGTCATTCTAGATTTCACTATAGTTGTTTCTTTTATGGCTTCAAAATGGACTCTGTTGTTAATTGGCATGCTTTTAGGCCTTTATAAAAACAGACTCACCCTGTGTATAGCTTTTATATATTTTAATATGATTACACAGTCTTTCAGGGGCAACCTTTTTCAAAACAATATGAATCATTGAGGCTGTCAGATCACTACTCTCTTCCAGGCTG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate