Basic Information
VIS ID
TVIS30016773
Fusion event
HIV-SLC25A14 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
129500712/130366738 (Hg38)
End
129501028/130366738 (Hg38)
Orient
+
Location type
Intronic
Target gene
SLC25A14
miRNAs that regulate target gene
hsa-mir-331-3p ; hsa-mir-182-5p
Nearest miRNA
hsa-let-7f-2/Upstream/8995685; hsa-mir-105-1/Downstream/3802640;
Nearest TSS
ENST00000429181/Upstream/1496; ENST00000370947/Downstream/18709;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/26767, chrX-CpG: 40/Downstream/35125
Upstream sequence
ggttagattataaaggatactgaatgctatattgaggtgcttggacttttttttaacttgtcagggagctgttgaaagtttttaatcagattagctttgc
Downstream sequence
atttagtaagtatggagtgggacctggaaatttgcatttttaataaattcccaggcaatactgatgttgctagtctggagaccacacttggagaaccact
Target sequence
attttaaatagattactttggctttatggagactggatctaccacagtggttcctcatcttgggtacacattggaatcacttgggagaactttcgcagctccctcctctaccttagaccaattaactcagaacctggggagtaaggtccaggtgtcaatattttaaactatatcaggtgactgcaatgttcacctaaggttgaagactactaaggggataagcctggagccatggttcttcaaagtttaacatgc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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