Basic Information
VIS ID
TVIS30016780
Fusion event
HIV-INTS6L integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
134686536/135552611 (Hg38)
End
134686570/135552611 (Hg38)
Orient
+
Location type
Intronic
Target gene
INTS6L
Nearest miRNA
hsa-let-7f-2/Upstream/1005900; hsa-mir-105-1/Downstream/998267;
Nearest TSS
ENST00000429181/Upstream/31618; ENST00000481429/Downstream/27274;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/30409, chrX-CpG: 93/Downstream/420901
Upstream sequence
TGACAGATTGGAAGTACAGGATAGTTTAGGCAGAGAACCATAAGTCCTGAAACTAATTTCTGTATTAGTGTAATATAATAAAACTCTTCGTCCTGTGGTA
Downstream sequence
TTGCAACTTGGATGAGACAAATGCATAGAGATATCTATCATACACTGGCTCTTCCAAGTGTTACACTTAAGCCAGAAGGATTTGCTGATTGGTTAATAGA
Target sequence
CAAATCACACTAAAAAATGTGTGTAATGTGGATT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate