Basic Information
VIS ID
TVIS30016792
Fusion event
HIV-CLIC2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q28
Reference genome
GRCh37/hg19
Start
154506621/155277332 (Hg38)
End
154506694/155277332 (Hg38)
Orient
+
Location type
Exonic
Target gene
CLIC2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-26b-5p
Nearest miRNA
hsa-let-7f-2/Upstream/389874; hsa-mir-1184-2/Downstream/105768;
Nearest TSS
ENST00000429181/Upstream/12743; ENST00000354514/Downstream/57095;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/12710, chrX-CpG: 41/Downstream/103254
Upstream sequence
TATATTGTTTTTTAAAATTATGTTTTATTTAATGAGTGCTTCTTCATTTAAAAATAATATAATCTGGTCACAAAGGCTACATTCTCATCTCTGACCATGA
Downstream sequence
AAAAATCATTCTTTAAGAATTTGCCTCTCTGATATGCTCACTCTCTGTATTTATTATTTATATCAGAAATAAACTCATGTATATATTAAACTAACAAAAA
Target sequence
GGTGGTCATAGTTCTAGGCGTCAAATGCTGTTCTATGACCAATTGATCTTGAGCTCTTCCTAGAGCTGATTTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate