Basic Information
VIS ID
TVIS30016793
Fusion event
HIV-chrY integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrY
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
2687831/2819790 (Hg38)
End
2687918/2819790 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-3690-2/Upstream/210536; hsa-mir-12120/Downstream/1786330;
Nearest TSS
ENST00000383070/Upstream/32091; ENST00000430575/Downstream/21696;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/29732, chrY-CpG: 129/Downstream/115133
Nearby gene
RPS4Y1(No orient, 21791)
Upstream sequence
gctgatacataaaactggactgtgcttacagcaggcagaaataataggccgggcacgtggcttatgcctgtaatcccagcacttgggaggctgaggtggg
Downstream sequence
tggtggcacgtacctgtaatcccagctacttgggaggctgaggcagaagaattgcttgaacccgggaggcagaggttgcagtgagctgagactgtgccat
Target sequence
caaatcacctgaggtcgggtgttcgagaccagcctgaccaacatggagaaaccccatctctactaaaaatacaaaatcagccaggtg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate