Basic Information
VIS ID
TVIS30016796
Fusion event
HIV-UTY integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrY
Cytoband
q11.221
Reference genome
GRCh37/hg19
Start
15474488/13362608 (Hg38)
End
15474300/13362608 (Hg38)
Orient
-
Location type
Intronic
Target gene
UTY
Nearest miRNA
hsa-mir-3690-2/Upstream/8756380; hsa-mir-12120/Downstream/116569;
Nearest TSS
ENST00000430575/Upstream/447112; ENST00000284856/Downstream/116896;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/457221, chrY-CpG: 33/Downstream/116771
Upstream sequence
TAAATAAATATTCAACACAGCCCTAAATAATGACAAATTATCAGATGCCTATGTGTTTTACTAACACCCAATGTCCTTATGCAGAGCTTTAATAACTTTT
Downstream sequence
AAAGTATAACTTTTAACACATCATTTTTTCAGCACAAATCACATTAGAAGCATTAAATCAGAAGGCAGTAGATGAGACTGAAAAAGGTAAAAGCAAAGAA
Target sequence
TATTTTAAGTGAGGCAATAACCAGTGTCATTACAAATGTATTACTACATCCCCATTTCACTTTGATATGTACAATCCAATTGAAAAGCTAAATAAATATTCAACACAGCCCTAAATAATGACAAATTATCAGATGCCTATGTGTTTTACTAACACCCAATGTCCTTATGCAGAGCTTTAATAACTTTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate