Basic Information
VIS ID
TVIS42000004
Fusion event
EBV-TMEM222 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
9446
Orient
+
Integrated sequence
TGCTCCAGGATGAAAGCCACTCAGTGTTGGCAAATGTGCACATCCATTTATAAGGATGTCAACTACAGTCAGAGAACCCCTTTGTGTTTGGTCCCCCCCC| |GTGTCACATGTGGAACAGGGCCCAGTTGGCAAGTTGTACCAACCAACTGAAGGGATTACATGCACTGCCCCGCGGGAAATACGTCCTACCCAGGAACCCG
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
GRCh37/hg19
Start
27648679/27322188 (Hg38)
End
27648679/27322188 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
TMEM222
miRNAs that regulate target gene
hsa-mir-218-5p
Nearest miRNA
hsa-mir-12136/Upstream/767595; hsa-mir-101-1/Downstream/3416968;
Nearest TSS
ENST00000473358/Upstream/28; ENST00000466759/Downstream/59;
Nearest CpG islands
chr1-CpG: 63/Target, None/Upstream, None/Downstream
Upstream sequence
TAGTCCCTGTTATACTAACTAAAATGTTTCCGGATCTTTCTTTTGCTATTTTACAAAAGTCTTCTTCCATAGGTTATGATGATGTCAGACAATGCTAAAG
Downstream sequence
gcaagaccaactggccatgggagacctatgttcactgttggtgatcttgtgctttatttctctatgtgagtaaagcattgttttatttggtacctgtgta
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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