VISDB Viral Integration Site DataBase

VIS ID

TVIS42000010

Fusion event

EBV-MED16 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

115300

Orient

-

Integrated sequence

CGTGGGGGCTAAAAATATGAGCAATTCCCCTGACCAGGGCCCTGGACTCACGAATGGCCCGACGGGTCTTAGAGAAAGAAACAGGCACCCTCGAGAGTGC| |CCCCGACCCGACCCCCACAGTGCCGCCAGTCCCTGCTCGGCCTCCGCCGCCTTCCCCACCGGCGCTGCCCCGGATGTTGCTGGGGTTCTCGAGGGCTGGG

Chromosome

chr19

Cytoband

p13.3

Reference genome

Start

End

873769/873769 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-197-3p ; hsa-mir-346 ; hsa-mir-24-3p ; hsa-mir-92a-3p ; hsa-mir-2861 ; hsa-mir-3648 ; hsa-mir-6749-5p ; hsa-mir-6795-3p ; hsa-mir-6807-5p ; hsa-mir-7151-3p ; hsa-mir-4653-3p ; hsa-mir-5095 ; hsa-mir-1287-5p ; hsa-mir-3135b ; hsa-mir-4438 ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-150-5p ; hsa-mir-6778-3p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-4715-3p ; hsa-mir-3064-3p ; hsa-mir-4493 ; hsa-mir-1915-5p ; hsa-mir-8485 ; hsa-mir-4747-3p ; hsa-mir-4707-3p ; hsa-mir-4755-3p ; hsa-mir-4258 ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-6508-3p ; hsa-mir-4726-5p ; hsa-mir-4640-5p ; hsa-mir-4284 ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-383-3p ; hsa-mir-6516-5p ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-6087 ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-1247-3p ; hsa-mir-4459 ; hsa-mir-665 ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-20b-3p ; hsa-mir-4768-3p ; hsa-mir-5690 ; hsa-mir-2114-5p ; hsa-mir-5588-3p ; hsa-mir-890 ; hsa-mir-1266-5p ; hsa-mir-3617-3p ; hsa-mir-3664-3p ; hsa-mir-383-5p ; hsa-mir-4310 ; hsa-mir-4433a-3p ; hsa-mir-4518 ; hsa-mir-7157-5p

Nearest miRNA

hsa-mir-1302-11/Upstream/60116; hsa-let-7e/Downstream/942390;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/2451, chr19-CpG: 20/Downstream/1445

Upstream sequence

TGAGAAAGGAGGGGATGTCTCCTCTCCTGGGAAGAGTGACGACATCTCTAGAAGCCAGGCATGAAAGAAGAGAATGAAAACTCCATCCGGTGTGGATTGA

Downstream sequence

CCCCCCCCCGGGGGCCGCTGTGCTCAGCACCAACCAGCTTCTCTCGGCCTGCAGGCCTTGGCGTGGGCAGGTCCCCATGCCAGGGCCACCAGTGCTCAGG