VISDB Viral Integration Site DataBase

VIS ID

TVIS42000022

Fusion event

EBV-CDC7 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

74470

Orient

+

Integrated sequence

TCAGAACCAGGCCGCAGCGGCTCTGTGAGGTCAGCCGCTTCTTGGGCAGGTGAAGCTGCAGTTCCACGAGAGAACCCGCCACGTGGTGGAGGGGCGAGGC| |GTTGTGGCACAAACAAAACAGGCGGAAGCCCTCGTCAGGCCGCGAGAGGATGGCATCGAGGATGGCCTCCGCAATGTCAGTGTTTGAGGCCACAAGGGCC

Chromosome

chr1

Cytoband

p22.1

Reference genome

Start

End

91985153/91519596 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-215-5p ; hsa-mir-101-3p ; hsa-mir-615-3p ; hsa-let-7a-5p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-29a-3p

Nearest miRNA

hsa-mir-101-1/Upstream/5161909; hsa-mir-11399/Downstream/2327236;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/18154, chr1-CpG: 38/Downstream/15870

Upstream sequence

ACTGAAAGGGATGGTAAAAAAGAATCGGCTGTCTTTGATGCTGTAATGGTTTGTTCCGGACATCATGTGTATCCCAACCTACCAAAAGAGTCCTTTCCAG

Downstream sequence

AGAGGGAAAAAAAACTCAACACTTTTGGCATAAGATTATTTCCAAGCGACTGTTTGCAGCTGTTGCAGCTGCCATCAGCATGAGCTGGTGGGAAAACAGC