Basic Information
VIS ID
TVIS42000029
Fusion event
EBV-UCHL5 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
67558
Orient
-
Integrated sequence
AAACTAATTTCTTTGAGCAAGAGAGTTCCGATTACACCATGCTGGTGGTAGATGACCTTTGAGTCAGGGTGGCTACTTGCTCAGGTTTCTGGGCATAAAT| |TCTCCTGCCTGCCTCTGCTCTGGTACGTTGGCTTCTGCTGCTGCTTGTGATCATGGAAACCACTCAGACTCTCCGCTTTAAGACCAAGGCCCTAGCCGTC
Host Sequence
Chromosome
chr1
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
193012276/193043146 (Hg38)
End
193012276/193043146 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1K
Target gene
UCHL5
miRNAs that regulate target gene
hsa-mir-5581-3p ; hsa-mir-657 ; hsa-mir-3665 ; hsa-mir-3185 ; hsa-mir-6872-3p ; hsa-mir-1322 ; hsa-mir-9500 ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-5584-5p ; hsa-mir-2681-5p ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-6883-3p ; hsa-mir-539-3p ; hsa-mir-485-3p ; hsa-mir-454-5p ; hsa-mir-6512-5p ; hsa-mir-1-5p
Nearest miRNA
hsa-mir-101-1/Upstream/326756; hsa-mir-1182/Downstream/93357;
Nearest TSS
ENST00000473358/Upstream/13571; ENST00000469214/Downstream/16071;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/234078, chr1-CpG: 94/Downstream/15945
Upstream sequence
tgaccccagggcacagtgaggtcataacatgcccccttctctctcaccatccctgctccAGCAGGCATGGGCTCCAGTCCCGAGCCCGGGCTTACATGGG
Downstream sequence
TGGCAGTGACACTGGGTGGTCAGGAGCTGGGATGTTAGTGTAGACGGACCTGATTTCAAGTCTTACCCAGGGCAAGACTTTGGGCAAGGTTCCATACTGG
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
Curate