Basic Information
VIS ID
TVIS42000040
Fusion event
EBV-SHLD2P1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
157708
Orient
-
Integrated sequence
CGGGCCGCGGATGGGGCTGGGGGCGATGGACTGCTGGGGGGTGAGGAAGTCGGAGTGGTAAGCTCCGTCAGGTTCTTGACGGTGGCCAACGAGCGCGGGG| |TCAGAGGTAGCCAAGCTAATAACAATCCTCCGCTCGTTATAAAATATGTAATGGCTTCCTGGCCCTTCGTGTAACGATCCTGGACGGCCTCGTACTTCTC
Host Sequence
Chromosome
chr10
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
46930509/46619106 (Hg38)
End
46930509/46619106 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10G
Target gene
SHLD2P1
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-1265/Upstream/1455018; hsa-mir-107/Downstream/2366406;
Nearest TSS
ENST00000439456/Upstream/7985; ENST00000605984/Downstream/13281;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/39481, chr10-CpG: 38/Downstream/16494
Upstream sequence
agaggaaagagcacgtgaggacgcagtgaggtggtgactatctTCTTCCACTTATTAAACTCACAGGCCACAAGATGAAATAACACGTTATGAAGAAAAC
Downstream sequence
TGCTTCATCTATAGGAAGTTGGGTGGTGCTGGTGTCATAGTTTACCAATGTACTACCTAATACTTGTTGTTTAAACACTTAATTTGGGATGGGGAGGAAC
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
Curate