VISDB Viral Integration Site DataBase

VIS ID

TVIS42000046

Fusion event

EBV-ZFYVE27 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

121481

Orient

+

Integrated sequence

CCCGGGACGGCCGTCTGGCGATAGGAGGAGTTGTACATGATGTCACCCAGAGAACCCAGCTGAGATGCCCAGGGATTCACAGTGCTCCGGTATTCATAGG| |CGGCATCCGGGCGAGAATGGTCATAGATGAGCCCCTCGGCAACCTCCTGATTGTAGTTTTCACAGGAGACCACACAGGCGGCCCGTCCCCTTGGAGAGTT

Chromosome

chr10

Cytoband

q24.2

Reference genome

Start

End

99505411/97745654 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA10D ; FRA10A ; FRA10B

Target gene

miRNAs that regulate target gene

hsa-mir-615-3p ; hsa-mir-193b-3p ; hsa-mir-423-3p ; hsa-mir-3915 ; hsa-mir-4725-3p ; hsa-mir-6780b-5p ; hsa-mir-4271 ; hsa-mir-5192 ; hsa-mir-4644 ; hsa-mir-185-5p ; hsa-mir-4306 ; hsa-mir-3202 ; hsa-mir-4533 ; hsa-mir-3135b ; hsa-mir-4693-3p ; hsa-mir-3928-3p ; hsa-mir-3179 ; hsa-mir-1252-5p ; hsa-mir-4267 ; hsa-mir-5586-5p ; hsa-mir-1207-3p ; hsa-mir-6783-5p ; hsa-mir-6876-5p ; hsa-mir-5586-3p ; hsa-mir-4476

Nearest miRNA

hsa-mir-107/Upstream/916890; hsa-mir-1287/Downstream/130159;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/7960, chr10-CpG: 91/Downstream/25752

Upstream sequence

TTTTCTATATTGCATTAAATGAAAAACAAGAAAGAAATGCAAGAGAAAAATGTTAATTTTTTTTGTGGGGTGGGTTCTCAAAAATGTTTTTTATTTACTA

Downstream sequence

GGGGGATATGAGACTTTCTACTCGGAATATCCTGAGTGTTGCGTGGATGTAAAACCCATTTCACAAGAGAAGATTGAGAGTGAGAGAGCCCTCATCAGCC