VISDB Viral Integration Site DataBase

VIS ID

TVIS42000047

Fusion event

EBV-WBP1L integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

148602

Orient

-

Integrated sequence

CAACTCAACTTGGGCACCTCGATAACCGGCTCGTGGCTCGTACAGACGATTGTTTGGCTCTGTAACTTGCCAGGGACGGCTGACGATGTGTTTAGTCTGC| |CACTTGCATCCGGCGCTTTGGTTACTCGGGAGACTAATGGGGGGTGTGGTATGGCACAGGCTGGGGGTGAGTCTGGGGATGTCCCTGGGCGTTGCTGCAG

Chromosome

chr10

Cytoband

q24.32

Reference genome

Start

End

104571975/102812218 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA10D ; FRA10A ; FRA10B

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-155-5p ; hsa-mir-19b-3p ; hsa-mir-760 ; hsa-mir-615-3p ; hsa-mir-320a ; hsa-mir-2110 ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-6733-5p ; hsa-mir-6739-5p ; hsa-mir-3153 ; hsa-mir-8089 ; hsa-mir-4700-5p ; hsa-mir-4667-5p ; hsa-mir-582-3p

Nearest miRNA

hsa-mir-107/Upstream/375634; hsa-mir-1307/Downstream/582035;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/97264, chr10-CpG: 28/Downstream/42025

Upstream sequence

agaggaaagagcacgtgaggacgcagtgaggtggtgactatctTCTTCCACTTATTAAACTCACAGGCCACAAGATGAAATAACACGTTATGAAGAAAAC

Downstream sequence

AGCGAGCGGCGCTTTGGGGGAGGGGTCGCGTAGGCGCCTCACCTGACCCTGCGGCCGTGCGGTTGCTGCTCCGGGGCAGGTCTCCTTCCAGGCCAGGGGC