VISDB Viral Integration Site DataBase

VIS ID

TVIS42000048

Fusion event

EBV-RBM20 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

2058

Orient

+

Integrated sequence

CTCAGCGTCAGGAGAGGGCCAGAGAACTGGCCCTCGTTGGCATTCTACTAGGAAACGGCGAGCAGGGTGAACACTTGGGCACGGAGAGTGCCCTGGAGGC| |CTCAGGCAACAACTATGTGTATGCCTACGGACCAGACTGGATGGCAAGGCCTTCCACATGGTCCGCGGAAATCCAGCAATTCCTGCGACTCCTGGGCGCC

Chromosome

chr10

Cytoband

q25.2

Reference genome

Start

End

112500824/110741066 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA10D ; FRA10A ; FRA10B

Target gene

miRNAs that regulate target gene

hsa-mir-1274b ; hsa-mir-296-3p ; hsa-mir-5680 ; hsa-mir-4789-3p ; hsa-mir-376c-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-106a-5p ; hsa-mir-526b-3p ; hsa-mir-106b-5p ; hsa-mir-17-5p ; hsa-mir-93-5p ; hsa-mir-20a-5p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-301b-3p ; hsa-mir-130a-3p ; hsa-mir-130b-3p ; hsa-mir-3666 ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-301a-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-6873-3p ; hsa-mir-29a-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-26a-2-3p ; hsa-mir-26a-1-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-1292-5p ; hsa-mir-181b-2-3p ; hsa-mir-181b-3p ; hsa-mir-204-3p ; hsa-mir-3191-5p ; hsa-mir-3192-5p ; hsa-mir-326 ; hsa-mir-330-5p ; hsa-mir-4314 ; hsa-mir-4420 ; hsa-mir-4471 ; hsa-mir-4646-5p ; hsa-mir-4688 ; hsa-mir-518c-5p ; hsa-mir-593-3p ; hsa-mir-619-5p ; hsa-mir-627-5p ; hsa-mir-6506-5p ; hsa-mir-653-3p ; hsa-mir-6743-5p ; hsa-mir-6764-3p ; hsa-mir-6824-3p ; hsa-mir-8059 ; hsa-mir-924

Nearest miRNA

hsa-mir-107/Upstream/6472661; hsa-mir-202/Downstream/157024;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/68398, chr10-CpG: 101/Downstream/130590

Upstream sequence

TTTGTTACTTGCAGCCATTGAGCCCTAACTCATGAACAGGAAGAGGGCCCACCAATCCAGAGATTGGAAGGCTACAAGAGCAGCTTAGGCAGAGCATTGA

Downstream sequence

GGTGATTATCCAGGGTTTTCGAAGTTACAGAGATCAAACAATTGTAGATCCCTTCAGTTCAAAACATAATGTGATTGGTAAGTGTTCTTGGTTTACTCGG