VISDB Viral Integration Site DataBase

VIS ID

TVIS42000052

Fusion event

EBV-PARVA integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

161068

Orient

+

Integrated sequence

CGTCTGCCCCCGGAGCCCTGCCCTCCTCCACCCAGCAGCAGCCCGGCCGAGGCCTGCGACGCGGTGCTGACCGGCTCGGCCACGCTGATAAAGTTGTCCT| |GGGCTGCCCCGGGCCCACCCCACACTCCCTCCAGAAAGTCCCGAGCGGCCTCCGCCGTCCACTCTATCCCGCTGGAGGCAATGGTCGCCAGGGTTTCTAG

Chromosome

chr11

Cytoband

p15.3

Reference genome

Start

End

12430579/12409032 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-633 ; hsa-mir-3160-5p ; hsa-mir-631 ; hsa-mir-3661 ; hsa-mir-1322 ; hsa-mir-1272 ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-4485-5p ; hsa-mir-483-3p ; hsa-mir-5195-5p ; hsa-mir-24-1-5p ; hsa-mir-24-2-5p ; hsa-mir-888-5p

Nearest miRNA

hsa-mir-210/Upstream/245265; hsa-let-7a-2/Downstream/3560501;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/30716, chr11-CpG: 178/Downstream/264835

Upstream sequence

caatctcaactcctgtctcctgtgtcacctgctcagagaagctgtcccAAtttctttttttttttttttttgagacggactctcactctgttgtccaggc

Downstream sequence

TTTCTCAACAGCATCTGCTTTCTTATCAGAGTTCTTTCTGAAACATAAACTTGACCTCGTCATTTCCCTACTTGTATGATCACCATGGGTTGCTCCTGCC