VISDB Viral Integration Site DataBase

VIS ID

TVIS42000053

Fusion event

EBV-UEVLD integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

66139

Orient

-

Integrated sequence

GGGAAGCTTTGAATCTTGTCGGGGGCCGTGTCTCCTGCCTCCCGGAGGCTCTGCGGCAGCGCTACCTGCGTTTCCAAACGGCCTTTGATTACAACCAGGA| |GGACCTGATTCAGATGTCCCGGGACAGGGCCCCCTTTGTGGACCAGAGCCAATCTCACAGCCTGTTTTTGCGTGAGGAAGATGCCGCGCGGGCCAGCACG

Chromosome

chr11

Cytoband

p15.1

Reference genome

Start

End

18610435/18588888 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA11C ; FRA11I

Target gene

miRNAs that regulate target gene

hsa-mir-20a-5p ; hsa-mir-4666b ; hsa-mir-627-3p ; hsa-mir-4495 ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-4282 ; hsa-mir-5096 ; hsa-mir-7641 ; hsa-mir-197-3p ; hsa-mir-4695-3p ; hsa-mir-4662a-5p ; hsa-mir-4716-5p ; hsa-mir-6823-5p ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p ; hsa-mir-3591-5p ; hsa-mir-4477a ; hsa-mir-4473 ; hsa-mir-4671-3p ; hsa-mir-6832-3p ; hsa-mir-519e-3p ; hsa-mir-515-3p ; hsa-mir-33b-3p ; hsa-mir-371a-3p ; hsa-mir-371b-3p ; hsa-mir-7109-3p ; hsa-mir-5698 ; hsa-mir-1178-3p ; hsa-mir-4634 ; hsa-mir-6828-3p ; hsa-mir-6499-3p ; hsa-mir-767-3p ; hsa-mir-2276-3p ; hsa-mir-6728-3p ; hsa-mir-1304-3p ; hsa-mir-5693 ; hsa-mir-6890-3p ; hsa-mir-378a-5p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-1976 ; hsa-mir-3653-5p

Nearest miRNA

hsa-mir-210/Upstream/201028; hsa-let-7a-2/Downstream/986422;

Nearest TSS

Nearest CpG islands

chr11-CpG: 38/Target, None/Upstream, None/Downstream

Upstream sequence

tcaatagagaagatacatgctagatggtgataagtgctaaggaggaaaagtgggaaaggggttaaagagtattggaggaggagcagttagaagggttggc

Downstream sequence

tggagtgcagtggcacgatctcacctcactacagcctccgcttcccgggttcaagcaattctcatgcctcagcctcctaagtagctgggactacaggtgc