Basic Information
VIS ID
TVIS42000059
Fusion event
EBV-ME3 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
100843
Orient
+
Integrated sequence
GAAGCCCGACCAGGGTCTTGTACTGGGCCAGGGGATCGAGGAAGACCTCGCACTCCACCGGGCAGGTAAACATGGTCACCCCGCCCCCATCTCCCCCGGT| |TCCCCGCGCGGCACGCCCCTGCCCGGCAGTCTTGAGCGTGGCATGGAGGGTGGTGAGGAAGGTCTTGACCTCGGCGTGGGAGAGGAAGAGCCGGGTCCAG
Host Sequence
Chromosome
chr11
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
86293951/86582909 (Hg38)
End
86293951/86582909 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11F
Target gene
ME3
miRNAs that regulate target gene
hsa-mir-30a-5p
Nearest miRNA
hsa-mir-10392/Upstream/304511; hsa-let-7a-2/Downstream/1593593;
Nearest TSS
ENST00000527297/Upstream/84785; ENST00000526206/Downstream/88913;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/151355, chr11-CpG: 82/Downstream/88744
Upstream sequence
CCACCCGCATTCAACGCCCCGGGCTCAGCCGCGGCTGCGCCCGGAATCCGGGGCCTCTCCTTCGTGACCCCGGAGTGGGCAAGTGACGAGGGCACGGCCA
Downstream sequence
GAAACGCATTGGCGTCAAGGAAACCACGACCCATCTTCCTGGAAGGAAACTTGGGGACACTTATGAAGAGAAGACTAGGAAGGACCGGAGTAGAAGCACT
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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