Basic Information
VIS ID
TVIS42000064
Fusion event
EBV-CPNE8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
105488
Orient
+
Integrated sequence
GGTGCCATAGCGGTGAAGGGCCCGCAGCCAGGTTTGCGCGTCCCGCGCCTGCCCTCCGCCATCAGGCGTTCCCACGGGGGCGCCCCTGGCAGAGAGGTGG| |CAGCGGGCCAATTCGTAGAGCCACCAAGTGGCATCAGCCTCAAGGATGGCTGTGGCCTCCGCGCGCCCGACCACCGTCGTCTCGTCCTCCCCCCCTCCCT
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
GRCh37/hg19
Start
39265457/38871655 (Hg38)
End
39265457/38871655 (Hg38)
Orient
-
Location type
Intronic
Target gene
CPNE8
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-124-3p ; hsa-mir-16-5p ; hsa-mir-8485 ; hsa-mir-4719
Nearest miRNA
hsa-mir-1244-3/Upstream/12997576; hsa-let-7i/Downstream/3452045;
Nearest TSS
ENST00000382841/Upstream/103938; ENST00000551152/Downstream/33976;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/554814, chr12-CpG: 29/Downstream/33791
Upstream sequence
CTCTAACTTCTTCTGCAGCTGGGCGATGGAGTGAGCTGATTTCTGATTCTTCTTCTCAAAGACTTGCTTGATACGTCCCGCCTGCTGCTTGTCTGCGTTG
Downstream sequence
gggattacaggtgcccaccaccatgcccggctaatttttgtatttttagtagagacagggtttcaccattttggccaggctggtctcgaacccctgacct
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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