VISDB Viral Integration Site DataBase

VIS ID

TVIS42000066

Fusion event

EBV-CBX5 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

136760

Orient

-

Integrated sequence

TACTTTACCTCCCCAGGAGGTTACTACGCCGGGCCCGCGGGCGGGGACCCGGGTGCCTTCTTGGCGATGGACGCTCACACCTACCACCCCCACCCACACC| |CCCCTCCGGCCTACTTTGGCTTGCCGGGCCTCTTTGGCCCCCCTCCACCCGTGCCTCCTTACTACGGATCCCACTTGCGGGCAGACTACGTCCCCGCTCC

Chromosome

chr12

Cytoband

q13.13

Reference genome

Start

End

54652979/54259195 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-1-3p ; hsa-mir-484 ; hsa-mir-339-5p ; hsa-mir-320a ; hsa-mir-197-3p ; hsa-mir-92a-3p ; hsa-let-7e-5p ; hsa-let-7b-5p ; hsa-mir-345-5p ; hsa-mir-4795-3p ; hsa-mir-1343-3p ; hsa-mir-6716-5p ; hsa-mir-6783-3p ; hsa-mir-6852-5p ; hsa-mir-6736-3p ; hsa-mir-548p ; hsa-mir-4438 ; hsa-mir-4635 ; hsa-mir-488-3p ; hsa-mir-583 ; hsa-mir-4650-5p ; hsa-mir-1304-5p ; hsa-mir-6878-3p ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-6721-5p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-4763-3p ; hsa-mir-6781-3p ; hsa-mir-1207-5p ; hsa-mir-2682-3p ; hsa-mir-4721 ; hsa-mir-3616-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-548at-5p ; hsa-mir-376a-2-5p ; hsa-mir-202-3p ; hsa-mir-6831-5p ; hsa-mir-4668-3p ; hsa-mir-3927-3p ; hsa-let-7a-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7g-5p ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-mir-4500 ; hsa-let-7f-5p ; hsa-mir-514b-3p ; hsa-mir-514a-3p ; hsa-mir-4477a ; hsa-mir-4316 ; hsa-mir-1294 ; hsa-mir-4677-3p ; hsa-mir-16-1-3p ; hsa-mir-126-5p ; hsa-mir-5683 ; hsa-mir-370-5p ; hsa-mir-383-3p ; hsa-mir-3065-3p ; hsa-mir-5089-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-4252 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-3937 ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-6504-3p ; hsa-mir-512-3p ; hsa-mir-449b-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-6771-5p ; hsa-mir-7977 ; hsa-mir-566 ; hsa-mir-4743-5p ; hsa-mir-4268 ; hsa-mir-6720-3p ; hsa-mir-20b-3p ; hsa-mir-6746-5p ; hsa-mir-4267 ; hsa-mir-2114-5p ; hsa-mir-5588-3p ; hsa-mir-4256 ; hsa-mir-6505-3p ; hsa-mir-617 ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-4735-5p ; hsa-mir-6742-3p ; hsa-mir-939-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-1180-5p ; hsa-mir-1343-5p ; hsa-mir-2110 ; hsa-mir-3150a-3p ; hsa-mir-3175 ; hsa-mir-3908 ; hsa-mir-450a-2-3p ; hsa-mir-509-3p ; hsa-mir-6763-5p ; hsa-mir-6810-5p ; hsa-mir-6825-5p ; hsa-mir-6857-5p ; hsa-mir-7114-3p ; hsa-mir-7973 ; hsa-mir-92a-1-5p ; hsa-mir-939-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/27719; hsa-let-7i/Downstream/78021;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/40941, chr12-CpG: 18/Downstream/20343

Nearest cancer related gene

CBX5(TSG, No orient, 0)

Upstream sequence

AATAATATGGGGAAAATACAGAGTTGCTTGAATGCTTATCACTTTATTACTGCAATCATAAATGATAGTAATTTAAATTAGTCCTTCACATTGATATGTG

Downstream sequence

gcatgcttgtattcccagctactcgggaggctggggcaagagaatcgcttgaacctgggaggcggaggttgcagtgagccgagattgcatcactgcactc