Basic Information
VIS ID
TVIS42000071
Fusion event
EBV-chr12 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
1690
Orient
-
Integrated sequence
GTCATTAGATGCTGCCGCTACTGCTGCTACTACTGCCTTACACTGGAAAGTGAGGAGCGCCCACCGACCCCATATCGCAACACTGTATAAAGGTAAGTAT| |TATTAAATTTTAGAGACACTATCACGTGTAACTTGACGTGCAAGGATGGAAGAGAGGGGCAGGGAAACGCAAATGCCGGTTGCCCGGTATGGGGGCCCGT
Host Sequence
Chromosome
chr12
Cytoband
q24.32
Reference genome
GRCh37/hg19
Start
128069003/127584458 (Hg38)
End
128069003/127584458 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA12E
Nearest miRNA
hsa-let-7i/Upstream/2668799; hsa-mir-3612/Downstream/709634;
Nearest TSS
ENST00000382841/Upstream/244386; ENST00000535247/Downstream/13710;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/128096, chr12-CpG: 18/Downstream/176589
Upstream sequence
GCTTCATATTTTGTTCATGGTATTTTTTAATAATGTCAAATCAATGCTTCTTTTTTTGGTGTTAATTTTTTATTGTTTAGAAACTGTACCACCACCTGTG
Downstream sequence
CAATCTGTGATGTAAATTAAGATATGTCAAAGTACTTAAAGATACTTTTATATGATTATATAATATATGACATAATTTACTCTGTATCTAAGTGAAATAT
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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