VISDB Viral Integration Site DataBase

VIS ID

TVIS42000072

Fusion event

EBV-TMEM132C integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

74303

Orient

+

Integrated sequence

GGCATCCCCCTGTGGCTGTTTCTTAGCGCTCAGTGTGAGCAGTTCCACGAGGGGCGTGAGCGAGCGCAGGGCCCCCGCGCGATCTAGGTAGGTGGATAGA| |CGGTCCGCGGTGAGCGGCGTGAGGCCGCGCAGGAAGGGGAAGGCCTCCTCCGCCGGCAGGTGCAGCGTCAGAACCAGGCCGCAGCGGCTCTGTGAGGTCA

Chromosome

chr12

Cytoband

q24.32

Reference genome

Start

End

129069719/128585174 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-7156-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-1184 ; hsa-mir-1976 ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-4742-5p ; hsa-mir-141-5p

Nearest miRNA

hsa-let-7i/Upstream/290996; hsa-mir-6763/Downstream/3996823;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/169654, chr12-CpG: 21/Downstream/120016

Upstream sequence

AAGGTAGGAGAATTGTTGCAACAGGGAGGACAAAAGAGAAAATGGGTCTGAATAAAAAGGCTGGCTTATCCAAGCATGGATTTTTCTTTTTTATGAAAGA

Downstream sequence

GAATTCATAGCACTGGATGACATTAAGTTATGAAGATACGGGAGAGAAACTCAGGATGACTACAAAAATTGCAGTTTCATATTTTGGCTGGTAGTTTTAG