VISDB Viral Integration Site DataBase

VIS ID

TVIS42000075

Fusion event

EBV-FREM2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

150469

Orient

+

Integrated sequence

ACGGTGCGGCCCCAATACAACTCTCCGCTCGTTAGCTGGTAGAATATCCGCCCGGCGTCTAGGTTGTCACTTCGCTCGGCCGGCCAGAAGAGCGCAAGTC| |CAAGTCTGGTGCTGGGGCCGATGTGCAGCGGTTTGTGCCCGCAGTTGTAGACTGTCATTTTTATGGGCGAGTGGGCGGTCCACACGCGCGGGCGCAGCAC

Chromosome

chr13

Cytoband

q13.3

Reference genome

Start

End

39332184/38758047 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-29c-3p ; hsa-mir-615-3p ; hsa-mir-574-5p ; hsa-mir-1277-5p ; hsa-mir-297 ; hsa-mir-493-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-5580-3p ; hsa-mir-6888-3p ; hsa-mir-6873-3p ; hsa-mir-3120-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3613-3p ; hsa-mir-3675-3p ; hsa-mir-3664-5p

Nearest miRNA

hsa-mir-2276/Upstream/14595543; hsa-mir-1267/Downstream/905987;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/69885, chr13-CpG: 49/Downstream/279504

Upstream sequence

caatgaggataatgatagtagcactcttgcgggggggtgggggggttgtgagaattatataaattcacccatgtaaagtgcttacgacacagccggcaaa

Downstream sequence

taaaataaatacattaatcagtagcaattttCCCCTTCAAGTCCACCTTTATGCCACTGCCAGATTAATTTTCTTAAATTACTACATTCCATGTGTGATC