Basic Information
VIS ID
TVIS42000078
Fusion event
EBV-DIAPH3 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
131080
Orient
-
Integrated sequence
TGTATGACTTCCTTAAGTACACTAAAGATGCTGTTCTTATACAGCTTCTCGGCCACACCACTTCGAATTATGGGGGTGTGGCTTTGATGACATACTGTCG| |TGATTGTTGTTAGACCGGCACATACCTTCACAATGTCCTCGGGGGCAAAATACTGTGTTAGGAGCCAGGCACAGTAAACGGCGTGATATGCATCGTTGAC
Host Sequence
Chromosome
chr13
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
60448014/59873880 (Hg38)
End
60448014/59873880 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA13B ; FRA13C
Target gene
DIAPH3
miRNAs that regulate target gene
hsa-mir-155-5p
Nearest miRNA
hsa-mir-1297/Upstream/4699332; hsa-mir-1267/Downstream/1325918;
Nearest TSS
ENST00000623511/Upstream/12448; ENST00000435636/Downstream/138871;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/2239084, chr13-CpG: 52/Downstream/289646
Upstream sequence
atcagtgattgaagatcaaacgaatgatataaagtgagaagacaaaattagagaaaaaagagtgaaaagaaataaacaaagcctccaagaaatatggcac
Downstream sequence
tatgtgaaaagaccaaatctatgtttgattggtgttcctgaaagtgacggggagaatggatccaagttagaaaacactccaggatattatctaggagaac
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
Curate