Basic Information
VIS ID
TVIS42000083
Fusion event
EBV-KLHL33 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
100181
Orient
-
Integrated sequence
CATGTTGTTGGTAAATGTGCAGAAGGGGAGGTCCCTGAACTCCCTTCCGCCATAGCGGACGGCCACATCCAGGCATTGCCTGAAATAGGCCCTGAGGTCA| |TTATATATGTTTAACAGGGAGCAGAGGGGGGCAGAATTTGCGGCCGGGGGAGCCAGTACTCGGGCATAGAAGACAGCGGCGGGGCTCCGCTCCCCATCCC
Host Sequence
Chromosome
chr14
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
20903962/20435803 (Hg38)
End
20903962/20435803 (Hg38)
Orient
+
Location type
Intronic
Target gene
KLHL33
Nearest miRNA
hsa-mir-1185-1/Downstream/587511;
Nearest TSS
ENST00000550708/Upstream/161; ENST00000555435/Downstream/8;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/242, chr14-CpG: 87/Downstream/18778
Upstream sequence
tcccagctactcaggaggctgaagctggagaatcacttgaacccaggaggtggaggttgcagtgagcagagatcgcaccattgcattccagcctgggtga
Downstream sequence
ACGCTCATGCCGAGGTTTGCTGGATAGCTGCAGGTGAGCAGAGGCAAGACAGCCTGGCGTCAGAGCTGGGCCCAAAGAGGCCAGAGCAACCATGTCTCCA
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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