Basic Information
VIS ID
TVIS42000088
Fusion event
EBV-chr14 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
122121
Orient
+
Integrated sequence
GGATCTCATCGGTCCTGACCACGGTCATGGCCACCCCTGGGTGGATCTTGAGCTTGGCCTGGGCAATATAGGCCATGGGGGACATCTTGATGTGCATGGC| |GGTCATTCCACTGATTGAAACGAGGGAAGGAAGACATTCGGCCGCGTATTTGCCCATGGGCGAGCGGTGCCACTCCCGGTACTCTGCAAAGAGCTGCTCT
Host Sequence
Chromosome
chr14
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
63590122/63123404 (Hg38)
End
63590122/63123404 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA14B
Target gene
LOC105370531 ; PARP1P2
Nearest miRNA
hsa-mir-208a/Upstream/2474693; hsa-mir-1185-1/Downstream/971620;
Nearest TSS
ENST00000550708/Upstream/21367; ENST00000557133/Downstream/4810;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/77126, chr14-CpG: 103/Downstream/419423
Upstream sequence
cacctattctggaatagtgtacaaaaatcacatAGGCCATCCCGACTCCTAACTGAATCCCCTCTTCCACCGTCAGAGGACGAGGGCACTTTTTGGCATG
Downstream sequence
CAGGTAAATCTGAAGTATCTGCTGAAACTGAAATTCAATTTTAAGACTTCCTTGTGGTAATTGGGAGAGGTGGCCAAGTCACTCCCGATGGCTCTGGTAT
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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