VISDB Viral Integration Site DataBase

VIS ID

TVIS42000090

Fusion event

EBV-ESRRB integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

152946

Orient

+

Integrated sequence

GCTTCATGATCCCACCGCCTTTCCCGATGATGATGACAACCGCGGCTGTCTGAAGCGGCTGACGAAATCGGTTGAGATTCTGATGAGAGGCTTGGGGGGG| |TCTTTGCCCTCAAGGCGAGGCTCCTTCTCCTAGGAATGCCGAGCCCCCTGCACTAGCTTCGCTCCACTGGGGATCTTTGCCAGCCTTCATACTAGATTCA

Chromosome

chr14

Cytoband

q24.3

Reference genome

Start

End

76861445/76395102 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-19b-3p ; hsa-mir-6748-5p ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-5008-5p ; hsa-mir-4695-5p ; hsa-mir-552-3p ; hsa-mir-6768-5p

Nearest miRNA

hsa-mir-208a/Upstream/1914898; hsa-mir-1185-1/Downstream/871116;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/17599, chr14-CpG: 42/Downstream/18710

Nearest cancer related gene

ESRRB(TSG, No orient, 0)

Upstream sequence

CAGTAAGTATGATTATTTTCCAGGATACATATAAGAAGAGAGTAAAATCATATCTGCAGCTCCGTCTAAGTTTATTTTTTTTTTCTTTTGTCCCCCTTTT

Downstream sequence

GACAGTCAGCCCCTCGCCCAGTGGGAGGAGGAGATAGAGAGGTAAGAGCTACCTGAGAATTAAGCCATGTGCACTATCTGGCTCATGCTGGTCTTCCCGG