VISDB Viral Integration Site DataBase

VIS ID

TVIS42000092

Fusion event

EBV-NRXN3 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

158024

Orient

+

Integrated sequence

ACTTCCCTGTTTCTGTGGCGATGGTCGAGTCAAAGGTTTGCCAGTGTTGAAGCGGGCAGTAGGCTGTCCTGTTCTCGAGCTTCCAAGATAGCGTGTAAGT| |GCCCTTGTCCAGGAAGGCTCGGCGTTCGCCTTGCGGGTTCGTCCCTCGGTTGTCGTAGTCCACTATCTTGTAGTTAGTTCTCACGTGGAAGGAGTCTGCC

Chromosome

chr14

Cytoband

q31.1

Reference genome

Start

End

79949940/79483597 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-374b-5p ; hsa-mir-92a-3p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-6880-5p ; hsa-mir-3165 ; hsa-mir-8071 ; hsa-mir-505-5p ; hsa-mir-4795-5p ; hsa-mir-192-3p ; hsa-mir-5189-3p ; hsa-mir-4786-5p ; hsa-mir-1915-5p ; hsa-mir-3667-3p ; hsa-mir-6849-3p ; hsa-mir-665 ; hsa-mir-1304-5p ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-3664-3p ; hsa-mir-1282 ; hsa-mir-5707 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-4478 ; hsa-mir-3929 ; hsa-mir-4419b ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-4695-5p ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-5690 ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-1227-3p ; hsa-mir-1273a ; hsa-mir-4252 ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-1273g-3p ; hsa-mir-3940-3p ; hsa-mir-508-5p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-6807-5p ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-4257 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p

Nearest miRNA

hsa-mir-1260a/Upstream/2217307; hsa-mir-1185-1/Downstream/14464629;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/204051, chr14-CpG: 23/Downstream/378074

Upstream sequence

tccatcaaagggagaggaaaataaaccattttgaaatatggcagagcattctgttcttagcaaggtctgcccttgggagaaactatttaaccagagccaa

Downstream sequence

CAAGAGAAAAGCTGATATTGTCACATTGTGAGTCATAGTGACTCCCAAGGATGTATTTGTGTGGATGTGGTTGGTCAGAAGGCTTTGTGTGCACTGTGAC