Basic Information
VIS ID
TVIS42000097
Fusion event
EBV-EML1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
36442
Orient
+
Integrated sequence
CTCCATTAATTCCACTAACAATCTTTGTTGGGGAAAACACGGGGGTGCCCCCACCACTCCCACCACCCCCCCCACCACCACCCCCACCACCCCCACCACC| |CCCACCACCCCCACCACCCCCACCACCTCCACCACCTTCACCACCACCCCCGCCCCCACCACCCCCACCACCTCAGCGCAGGGATGCCTGGACACAAGAG
Host Sequence
Chromosome
chr14
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
100394116/99927779 (Hg38)
End
100394116/99927779 (Hg38)
Orient
-
Location type
Intronic
Target gene
EML1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-1229-3p ; hsa-mir-27b-3p
Nearest miRNA
hsa-mir-1260a/Upstream/4789793; hsa-mir-1185-1/Downstream/181640;
Nearest TSS
ENST00000550708/Upstream/13203; ENST00000553313/Downstream/8388;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/133887, chr14-CpG: 175/Downstream/43265
Upstream sequence
TCATAATTCTTGCTCTGAATGTTGAATGGGTTTCTAAAAAGTGATTAGTGAGTTGTCATTAGTTTTCAGTATGTTTGTGTTACATGAGCCTTATTTAAAG
Downstream sequence
agtggtggtggtattggtggtggggggggtgggggggtggtggtggtggtggtattggtggtggtgatggtggtggtggtagtggtagtagtggtggcgg
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
Curate