Basic Information
VIS ID
TVIS42000100
Fusion event
EBV-RYR3 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
120734
Orient
+
Integrated sequence
TTGGACTCTAACTTCACGGTGGCATGCTCTCGTCCAAATACCGGGGGCATAACACTGAGGCTCCCGGTCCCATGCCACTGGAAAAAGGGCTGGTACTTGT| |TCTTAATGGCGTAGGTCTGACCTGGAACAATCTTGGTGAGTATCAAACTGTCCACGCTAACCTCATCCAGCACGGCCAGGGTGCAATCAGACAGGTAGTT
Host Sequence
Chromosome
chr15
Cytoband
q14
Reference genome
GRCh37/hg19
Start
33997380/33705179 (Hg38)
End
33997380/33705179 (Hg38)
Orient
-
Location type
Intronic
Target gene
RYR3
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-mir-367-5p
Nearest miRNA
hsa-mir-1268a/Upstream/2640038; hsa-mir-10393/Downstream/676890;
Nearest TSS
ENST00000557528/Upstream/58890; ENST00000636417/Downstream/18973;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/393377, chr15-CpG: 114/Downstream/333189
Upstream sequence
TTGGCCTGGGAAGGAAGTAGGCAGAGCCCAGGTCTGGGGAATGACTTCTTACCTGCTGCAGCTCATACTCGGTGGAGAATCGTCGTGTCACTGCCTGGAT
Downstream sequence
CTTGAAAACTCTGCCCAATTCTGGCCCTTATTGATGCTTCCCTGACATTTTAAAGACAAAATCAAATCTGAACTCTAAGCAGAATATTATCTTTACTGGT
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
Curate