VISDB Viral Integration Site DataBase

VIS ID

TVIS42000103

Fusion event

EBV-THSD4 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

76203

Orient

-

Integrated sequence

AAGGTGAGCCGCCCTACACTAGCCTGCTGGAGCAACAGCTTGTCATTCTGGAAGGCGTAGCGTATGTGTGGACAGGCCTCCATGGTGATGATCTAACAGA| |CAGGGACGGCGGCGCTATATATAAGAGCCCAAGACCCGGCTCTCTTTACTGCGAAATGGGGAAGGTCCTAAGAAAGCCGTTTGCAAAGGCTGTGCCACTG

Chromosome

chr15

Cytoband

q23

Reference genome

Start

End

71866331/71573992 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-1909-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-512-3p ; hsa-mir-6768-3p ; hsa-mir-4484 ; hsa-mir-548an ; hsa-mir-4665-5p ; hsa-mir-4472 ; hsa-mir-1275 ; hsa-mir-4447 ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-6825-5p ; hsa-mir-7160-5p ; hsa-mir-6853-5p ; hsa-mir-6087 ; hsa-mir-4649-3p ; hsa-mir-1827 ; hsa-mir-670-5p ; hsa-mir-6848-5p ; hsa-mir-6846-5p ; hsa-mir-4697-5p ; hsa-mir-4488 ; hsa-mir-1237-5p ; hsa-mir-6816-5p ; hsa-mir-3196 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-6787-5p ; hsa-mir-663a ; hsa-mir-6882-3p ; hsa-mir-1908-5p ; hsa-mir-4749-5p ; hsa-mir-4706 ; hsa-mir-4312 ; hsa-mir-637 ; hsa-mir-6852-5p ; hsa-mir-6791-5p ; hsa-mir-4308 ; hsa-mir-4292 ; hsa-mir-4438 ; hsa-mir-3925-3p ; hsa-mir-4709-3p ; hsa-mir-665 ; hsa-mir-6863 ; hsa-mir-766-3p ; hsa-mir-873-5p

Nearest miRNA

hsa-mir-10393/Upstream/1494524; hsa-mir-11181/Downstream/1013225;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/358635, chr15-CpG: 18/Downstream/237859

Upstream sequence

CCCCAGGGCCTTTCAGGCAGGCTGAGGCTCAGGGCCTGCTCTCCCTGCCGGGTGTGCTGGGCAAGCACTTGGGGAGCCCTTGATGCTTCTCAGCAGTGTT

Downstream sequence

GCCTGCAGTTCAGATGGGTATTGACTGAAGAGGCGAAACCATAATTTCAAttcttgagaaagtagcgcagaacttctctagctcactactgtatcgcagt