VISDB Viral Integration Site DataBase

VIS ID

TVIS42000104

Fusion event

EBV-TBC1D2B integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

94631

Orient

-

Integrated sequence

CAAGCTTGTGGCTTTACGTGGTCATGTGCAGCTTGCATACGACGCCCGTGTCCTGACGCCTGACTTTCACGAAATCCCTGACCTCGATGACTCCGATGCT| |GTTTTCGCACGCACCTTATTGGCAGCCTTATTTCACCTCAATATGTTCTTTATTCTCAAAGATTACATAACACAAGACTCCATGAGCTTGAAGCAGGCCC

Chromosome

chr15

Cytoband

q25.1

Reference genome

Start

End

78301152/78008810 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-7-5p ; hsa-mir-26b-5p ; hsa-mir-484 ; hsa-mir-3915 ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-4668-5p ; hsa-mir-3202 ; hsa-mir-3928-3p ; hsa-mir-5093 ; hsa-mir-194-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-1252-3p ; hsa-mir-6890-3p ; hsa-mir-603 ; hsa-mir-8485

Nearest miRNA

hsa-mir-10393/Upstream/2246495; hsa-mir-11181/Downstream/1200978;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/64068, chr15-CpG: 103/Downstream/68365

Upstream sequence

ggggcctcttttatgctaaaatatcctcaaattttatctccagaccattgactttttgaagaatccaaaccttacagtcttatagaatggcccacactgt

Downstream sequence

CCTCAGTCACAAACAGCAGGCCATGACTGGGGACAGCCTCTGAGATGTGGCCTGCTGTCTTCAGGAATCAGTCTCTGAAGTCACATACACAAAGCAACCC