Basic Information
VIS ID
TVIS42000111
Fusion event
EBV-FCSK integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
90826
Orient
+
Integrated sequence
CACACAAGGCAAAGGAGCTTGCGATGGCCCTCCCAGGTCCTGATAGACTCTGGTAGCTTGGTCAAAAGCTTGTACAAAAGGCACCTGGTATGGGTCAGGT| |GTAAATTTTACATCTTCAGAAGTCGAGTTTGGGTCCATCATCTTCAGCAAAGATAGCAAAGGTGGCCGGCAAGGTGCAATGTTTAGTGAGTTACCTGTCT
Host Sequence
Chromosome
chr16
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
70506074/70472171 (Hg38)
End
70506074/70472171 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA16B
Target gene
FCSK
miRNAs that regulate target gene
hsa-mir-93-3p ; hsa-mir-618 ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1225/Upstream/441749; hsa-mir-11401/Downstream/6396765;
Nearest TSS
ENST00000527434/Upstream/17444; ENST00000573832/Downstream/2454;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/17260, chr16-CpG: 20/Downstream/952
Upstream sequence
AATAAGTTAAATATTTGATGGCTGTGCCTGATCTGAGAGAGAGTCCATGGTAAGAGATAGCACTAGGCAAAGCCACACTGGATGAACTTCAAACaaaaca
Downstream sequence
gccttgggctgcagcctgttgtggtgggctgggcctggaacccagggttctgctccagatttcaggcACCTTGGCGGGAGTGTTGGGGCTGCAGGGCTGA
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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