Basic Information
VIS ID
TVIS42000116
Fusion event
EBV-CCDC144A integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
109033
Orient
-
Integrated sequence
CCCCACTGTGGCGGACGTAGTCTCCAACAATTTTGTATTGGAGGAGCACCTGGTAGAAGTAGTTGTGCCGTGGATTGATGAAGATGTTGACTGGGACCCG| |GTCTTTAATACCAATGCGCCCCGCATTTTCGCTTGGGTCCGTCATTACGTAGAGCATAGACTCCACCCCCCTGTTGGCAGCTAGGCTGTCTGCCACCAGG
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
16577875/16674561 (Hg38)
End
16577875/16674561 (Hg38)
Orient
+
Location type
Intronic
Target gene
CCDC144A
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-676-3p ; hsa-mir-2355-5p ; hsa-mir-6731-3p ; hsa-mir-3938
Nearest miRNA
hsa-mir-1253/Upstream/392473; hsa-mir-10226/Downstream/1138919;
Nearest TSS
ENST00000595228/Upstream/20657; ENST00000478303/Downstream/14976;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/7340, chr17-CpG: 41/Downstream/14960
Upstream sequence
CCCAGGCCCTTGCTTCTACCTGCAGAGCTCTTCCTGTCTCCCTCTCACAGACCAACACAGGCATCCGTAAGAACTTGGAGCAGGAGATCATCCAGTACAA
Downstream sequence
agggagggaaagagaaagaaaaagtgagggaaggaagggagggagggaaggagggaAAGAAAGAAACCAAAGAAAGAAAATGTTTCAAGCTTTACAGTAG
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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