Basic Information
VIS ID
TVIS42000121
Fusion event
EBV-HOXB9 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
132055
Orient
+
Integrated sequence
TTCTTTTGTTTTAACGCGGAATGAGAAGAGGGCCTGCGGAAATTAGACTCATCCTCAGACTCACAGTCAGATTTGTCATCGAGCCCAAGGCCGGCCAGGC| |CCTCCTCAAAGCCTTTCTGGTACATGAAGCTCCGGCTCGTGGAGTCCGCACCTCCTTCTGTGCACGAAGTTTTGCGGAACCAGGAGAAGGGGTCTGGCGT
Host Sequence
Chromosome
chr17
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
46703776/48626414 (Hg38)
End
46703776/48626414 (Hg38)
Orient
+
Location type
Intronic
Target gene
HOXB9
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-10226/Upstream/46467; hsa-mir-1250/Downstream/6076;
Nearest TSS
ENST00000595228/Upstream/58; ENST00000462131/Downstream/2261;
Nearest CpG islands
chr17-CpG: 143/Target, None/Upstream, None/Downstream
Upstream sequence
AGCCTCCCAGCCCAGCTCTCCCTTCGTTCTCTCTCTTCtttttttttttttttttttttttttaatttttaatttttggagatggagtctcgctctgtca
Downstream sequence
TCAACTTCTCAGCCAACAAAGTACAGTGGAGCAGCCCGTCTCAGCTCTCCTTGCAAAATGATTGGTCAAAGTTTTTCCGACTGCCTGATAAAGCGTCAGC
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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