Basic Information
VIS ID
TVIS42000123
Fusion event
EBV-CUEDC1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
110601
Orient
-
Integrated sequence
CCCCCTCAAGATGTAGCACTTGCTCAAAAGGCAGAGGGGCTTATAGGTGTCCTTGGCTATAGAAAATGGTTCCCTCTGGCAATAGAGGCGATAGAGCTGC| |CGGCCCTTAGAAGACTTTAGCCGCACATCCAGCATCTTGTTGCGGTCGTGGAGGGAAGCAGTCCCATAATCAGTCAGGACCAGCCTACCCATGCCCCACA
Host Sequence
Chromosome
chr17
Cytoband
q22
Reference genome
GRCh37/hg19
Start
55988584/57911223 (Hg38)
End
55988584/57911223 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA17B
Target gene
CUEDC1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-9-5p
Nearest miRNA
hsa-mir-10226/Upstream/1019868; hsa-mir-1250/Downstream/420009;
Nearest TSS
ENST00000595228/Upstream/7834; ENST00000580184/Downstream/1110;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/25355, chr17-CpG: 161/Downstream/43259
Upstream sequence
TCTGTTAAAAAAAATTTTAagtgagccttgttagcaccactgcactccagcctgggtgatagagcaaaacctgtcgaaagaaagaggaaCGAagggaggg
Downstream sequence
atgctggcaccactggtccagggaccacacctGTCTCCCTAACTAAGCCCTGTCCATCCTTCAAGACCTCGCTCAAGTTCCCCTGTCCCATGAGGCAATC
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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