VISDB Viral Integration Site DataBase

VIS ID

TVIS42000125

Fusion event

EBV-BRIP1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

122661

Orient

+

Integrated sequence

CGGAGATCTCCAGCAGATCCCTGAGCGTCCCATTCTCCAAATTGTCGAGGATGTCCTCGTCCCTGGTAAAATGGTGGCTGAAGGCTGGCCCGTTGTAGGC| |CAGGGTCTGGGCCACGTGCTGAAAGTCCACCCCGAGGCCGCACATGTGGGCATTGGTGCAGGTTGGGAGGAAAACGTAGTAAAAGATCTTTTCCAGCACA

Chromosome

chr17

Cytoband

q23.2

Reference genome

Start

End

59804922/61727561 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-378a-5p ; hsa-mir-182-5p ; hsa-mir-34b-3p ; hsa-mir-3614-5p ; hsa-mir-3689d ; hsa-mir-3929 ; hsa-mir-4254 ; hsa-mir-4419b ; hsa-mir-4478 ; hsa-mir-455-3p ; hsa-mir-4649-3p ; hsa-mir-4722-5p ; hsa-mir-4768-3p ; hsa-mir-490-3p ; hsa-mir-493-3p ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-619-3p ; hsa-mir-6499-3p ; hsa-mir-6500-3p ; hsa-mir-6516-5p ; hsa-mir-6808-5p ; hsa-mir-6851-5p ; hsa-mir-6893-5p ; hsa-mir-7160-5p ; hsa-mir-7854-3p ; hsa-mir-940

Nearest miRNA

hsa-mir-10226/Upstream/1684456; hsa-mir-1250/Downstream/1216654;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/265088, chr17-CpG: 21/Downstream/135903

Upstream sequence

GTACGTACTTGAAAGTTTTACCTTTGATGTGTAATCCTTACTTTTGATGCGGCCTCCCGTGATCTCCGCATCTTAAAGGCCAAAACGTGAGAAACTAAAG

Downstream sequence

tttaggaccagccagggcaacatagcaagaccctgtctctacaaaataaaaattagctgggcatggtggtaggagtctgtagtcccagctacttaggagg