Basic Information
VIS ID
TVIS42000133
Fusion event
EBV-CCDC178 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
150354
Orient
-
Integrated sequence
GGCTGTTCCTGAACGACGAGCGCCGGGACGCTAGTGCTGCATGGGCTCCTCCGGGGTAAGCTTCGGCCATGGCCGGAGCTCGTCGACGGGCAAGGTGAGA| |GTCGGGGGGCGGGCGACGGTGCGGCCCCAATACAACTCTCCGCTCGTTAGCTGGTAGAATATCCGCCCGGCGTCTAGGTTGTCACTTCGCTCGGCCGGCC
Host Sequence
Chromosome
chr18
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
30960356/33380392 (Hg38)
End
30960356/33380392 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA18A
Target gene
CCDC178
Nearest miRNA
hsa-mir-1-2/Upstream/3081432; hsa-mir-122/Downstream/2211345;
Nearest TSS
ENST00000575820/Upstream/34170; ENST00000647014/Downstream/31720;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/608053, chr18-CpG: 45/Downstream/60154
Upstream sequence
caaagtttggctatgccatgacttgttgaggattactttgggtttgtcaagtttgtggttcactcagcttcttgaatcttctgccaaatttaggaagctt
Downstream sequence
gaatggctgagtttgtgtgcacccagattaaaaatggcctcctgctctcagtgctgagtctaagaaagtacctgtagcttttcccagtgtctttccctca
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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