VISDB Viral Integration Site DataBase

VIS ID

TVIS42000138

Fusion event

EBV-CRTC1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

102133

Orient

+

Integrated sequence

ACGTCCAGGGACAGACCATCTACGCCAACCTCCGCAACCCCGGAGTCTTCTCGAGGCAGGTGTTTACCCATTTGTTTAAACGAGCCATCTCTCATTGCAC| |GTACGATGACGTGCTACATGACTGGAACAAGTTCGAGGCCTGCATCCAGAAGCGATGGCCGAGCGATGACTCGTGTGCGAGCCGGTTTCGTGAGTCCACC

Chromosome

chr19

Cytoband

p13.11

Reference genome

Start

End

18860049/18749239 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-125b-5p ; hsa-mir-4638-3p ; hsa-mir-4787-3p ; hsa-mir-132-3p ; hsa-mir-212-3p ; hsa-mir-4696 ; hsa-mir-520f-5p ; hsa-mir-3675-3p ; hsa-mir-451b ; hsa-mir-3667-5p ; hsa-mir-3120-3p ; hsa-mir-7111-3p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-6862-5p ; hsa-mir-4253 ; hsa-mir-3945 ; hsa-mir-324-5p ; hsa-mir-6134 ; hsa-mir-6845-3p ; hsa-mir-6769b-3p ; hsa-mir-3183 ; hsa-mir-4723-3p ; hsa-mir-5193 ; hsa-mir-4667-3p ; hsa-mir-1470

Nearest miRNA

hsa-mir-10395/Upstream/362605; hsa-let-7e/Downstream/685824;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/29307, chr19-CpG: 22/Downstream/12970

Nearest cancer related gene

CRTC1(OG, No orient, 0)

Upstream sequence

GAGACTCTCTGGGGCCCCCGCAAGGGCCCGTGCGGCCTGGAGCGATCATCTTGGCGCTCCCTTCTGGAAAAGGGGCTTTTGTCCTCCAAGAGCACATGGA

Downstream sequence

CATTCCTTCCGGGGCCTTCTCCTAGCCCATTCCACCTGTCACACTGGGTTTGTGTGACACTGAGCATCCTAGAGGGCACAGTCACCTGATTGTGTTTGTC