VISDB Viral Integration Site DataBase

VIS ID

TVIS42000146

Fusion event

EBV-RASGRP3 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

97577

Orient

+

Integrated sequence

TGCCTCCCTGGTTTCCACCTATGGTGGAAGGGGCTGCCGCGGAGGGTGATGACGGAGATGACGGAGATGAAGGAGGTGATGGAGATGAGGGTGAGGAAGG| |GCAGGAGTGATGTAACTTGTTAGGAGACGCCCTCAATCGTATTAAAAGCCGTGTATTCCCCCGCACTAAAGAATAAATCCCCAGTAGACATCATGCGTGC

Chromosome

chr2

Cytoband

p22.3

Reference genome

Start

End

33784893/33559826 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-26a-5p ; hsa-mir-26b-5p ; hsa-mir-6824-5p ; hsa-mir-7106-5p ; hsa-mir-6825-5p ; hsa-mir-765 ; hsa-mir-766-5p ; hsa-mir-6782-5p ; hsa-mir-6783-5p ; hsa-mir-708-3p ; hsa-mir-335-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4264 ; hsa-mir-138-2-3p ; hsa-mir-4267 ; hsa-mir-1910-5p ; hsa-mir-455-3p ; hsa-mir-5588-3p ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a ; hsa-mir-4438 ; hsa-mir-409-3p

Nearest miRNA

hsa-mir-1301/Upstream/141262; hsa-mir-10b/Downstream/1911579;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/611729, chr2-CpG: 52/Downstream/39417

Upstream sequence

GTTTGGAGGGGGTGTTCCAGGGGGCCTCCGTGGCTCTGGAACTAGACTGATGACTTTTGGAGAATGAGCTCCAGAGAAACTGGCCTCTTTGGGCCAGGGC

Downstream sequence

ATGGGTGGTCCTCCACATTCCACTCTTCAGGAGACCTAAACACACGTCTCCATACATTTCCCATGATGAGAAAAACTCCAGTGACCTTTAGCCAGAAATT