VISDB Viral Integration Site DataBase

VIS ID

TVIS42000161

Fusion event

EBV-PARD3B integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

60096

Orient

+

Integrated sequence

GAGGGGAGGTGGGGTGTCTGCTCCCCCCTGCGGAAGCCGCCTGGGTGCGGGGATGAAGACAGGTGGTGGGCGGGCGTCTCGCCGGACTATGGCCTCGGCA| |CGCTCGGCGTCGATGGCGGGTGGCTGGAACAGGCGGGCGAATGTGTAATCCCGGAACCGGTAGGCGACGCTGCGCCTGAGGGCGCCCGTCAGGCTGTATC

Chromosome

chr2

Cytoband

q33.3

Reference genome

Start

End

206002772/205138048 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6873-3p ; hsa-mir-3941 ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6758-3p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-3180-5p ; hsa-mir-4642 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-891a-3p ; hsa-mir-3688-5p ; hsa-mir-4267

Nearest miRNA

hsa-mir-10b/Upstream/16004937; hsa-mir-1244-1/Downstream/1645186;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/591861, chr2-CpG: 91/Downstream/543831

Upstream sequence

gacattttaagctctcacttatagtgagaaaagcaatcttcagcaaggtgatgacttgtccaaggGAAGACATGGTCGCCCTTGTTCCTTGGGAGATTTT

Downstream sequence

GCACTGTTCTATAGCCGAATAAGTATTGGTCAGGGATGGAAGATTCAAGTTATCAGCCCAGGACTGTCAGTAGATGGTTGAGTTTTGAATGGTCGTTTAA