Basic Information
VIS ID
TVIS42000167
Fusion event
EBV-DOCK10 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
117964
Orient
+
Integrated sequence
CAACACCATCCAGCTCTCCTTCGATCCGGTCCTCTATCTCATCTCCCAGATCAGGGCCATCAAGCCCATCCCTCTCCGCGACGGTACCTACACCTACACC| |GGCAAGCAGCGCAACCTCTCTGACGACGTGCTGGTTGCGCTAGTCATGGCTCATTTTCTCGCAACAACACAGAAGCACACGTTCAAGAAAGTTCATTAAA
Host Sequence
Chromosome
chr2
Cytoband
q36.2
Reference genome
GRCh37/hg19
Start
225903299/225038582 (Hg38)
End
225903299/225038582 (Hg38)
Orient
+
Location type
Intronic
Target gene
DOCK10
miRNAs that regulate target gene
hsa-mir-142-3p ; hsa-mir-132-3p ; hsa-mir-26b-5p ; hsa-mir-21-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-10b/Upstream/28042; hsa-mir-1244-1/Downstream/1620128;
Nearest TSS
ENST00000437798/Upstream/56155; ENST00000636099/Downstream/3802;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/452811, chr2-CpG: 114/Downstream/3354
Upstream sequence
CTGACCCCAGGTCCCCAGGATGGACAGCCATCCTGTTTGGTAAGGAGTCAGAGGCAGCTATACTCAGTATGCTCTCAgttctcaaacctggctgcacact
Downstream sequence
AACCTCCTGGTTAAGTATAATCACTTCCGGCAGGATGCTTTCTCTTTAAAATGAGTTAATAACAAAATTAGATACAATTAAAAAGGAGTTGCAAAGGAGT
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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