Basic Information
VIS ID
TVIS42000172
Fusion event
EBV-TASP1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
71142
Orient
+
Integrated sequence
GTTGGTTGACTTGGTGAAAAACTCACGTAGTGTCTTGTAGCTCCTGCGCAGCTCGTGTCTGGGTTGCACTTTCTGCCAGGCTCCAATCTCTGGATGGGCG| |GCCACCGCCAGCATCGACTGTAGGAACGGGTCTTGGATGGGCTCTAGGGTCAGAGAGGCCAGGGGGCTGGGCAAGGTGACAAATGTAATCTTGGAGACAG
Host Sequence
Chromosome
chr20
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
13325481/13344834 (Hg38)
End
13325481/13344834 (Hg38)
Orient
+
Location type
Intronic
Target gene
TASP1
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-4503 ; hsa-mir-100-3p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/2695139; hsa-mir-1-1/Downstream/5125781;
Nearest TSS
ENST00000382410/Upstream/99465; ENST00000469177/Downstream/23869;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/45534, chr20-CpG: 43/Downstream/293804
Upstream sequence
cctcttgggactctcacagataAAACGTTATGTGCAGTTGTTTATCCATAGaaatatttaataatatttataCAGATTTTAAGTTTTGTCTAAAAATACA
Downstream sequence
GGCTGGCATGATTCATGGCCACAGCAGGCCCAGAAATTGGTCCCAGTGGTCTCCAAGGTTTCTCTGGCTTGAAGCACATCGAAGGCCCTCAGGCTCCCCG
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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