Basic Information
VIS ID
TVIS42000182
Fusion event
EBV-C21orf91-OT1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
123591
Orient
+
Integrated sequence
CAGCCCTGTGCCTGGCCCTCTCCCCGGCATCCCTGCCAATGTAAATATCATAAAGGGGGTGCAGCTCCAGCCGCAGCAGGTCATAATTGGACGGGTGGAG| |GAAGTCTTCGGTGGGCAGCCCGCACTTGAGAGCTATATCTGTCACGGGGGCTGCATACTTGTTATCATAGAACTCGTCCACAATAACAAGCACATTCATG
Host Sequence
Chromosome
chr21
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
19154827/17782510 (Hg38)
End
19154827/17782510 (Hg38)
Orient
-
Location type
Intronic
Target gene
C21orf91-OT1
Nearest miRNA
hsa-let-7c/Upstream/1192185; hsa-mir-155/Downstream/903580;
Nearest TSS
ENST00000624081/Upstream/122126; ENST00000428689/Downstream/9999;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/169131, chr21-CpG: 118/Downstream/36268
Upstream sequence
GCTTGTCCACAGCAAGATGGCCAGCAACTTGGTTATTTACCCAGTTAGTCTTGGGGAACACTAGAGCTCTTCCAATAGCTGGGACTATTTAAATTTTTTC
Downstream sequence
AAGGAAACATATGCTGTGGGTTGGTGGTAGATGGGATTCAGGAGGATCCTTCTCTTATACAAGATGACTTTCTGGATAGGTGTTTGTGGGGTACAGAGGG
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
Curate